Nicotine is the psychoactive chemical found in several plants, including tobacco. Nicotine in its purest form is an odourless, colourless liquid – a poison. It is one of the most addictive substances in the world which explains why it is so hard for people to give it up. Traditionally tobacco is smoked in a cigarette, cigar or a pipe. It is also produced synthetically and used for e-cigarette refills, vaping appears a safer option than cigarettes. In either form, it is ingested to stimulate the central nervous system and causes dependency. Smoking cigarettes regularly can cause lung cancer and heart disease – it increases blood pressure and heart rate.