Over the years many medicinal drugs have shifted from legal prescribed use to illegal misuse. Many years ago it was amphetamines but these days it is more likely to be valium type drugs (Benzos) or strong painkillers like Pregablin. Many more of these substances are being prescribed so there are more being misused. The harms are not very different, risk of collapse, overdose, getting ill from mixing with other drugs especially alcohol. Regular use of a drug like Gabapentin can cause dependence and there are many drug deaths related to taking these substances.